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Rina ShahClass of 2001- Present Union Hill H.S. + Rutgers University Topic: Isolation, Detection, and Cellular & Molecular Characterization of Circulating Sin Tumor Cells from Cancer Patients About: My most intellectually and emotionally fulfilling activity was conducting medical research at Memorial Sloan-Kettering Cancer Center because it enabled me to understand my younger sister’s illness and realize how medical research can be applied to help mankind. How often do you encounter a 16-year-old high school student eagerly awaiting her summer vacation so that she can start volunteering at a hospital? I spent two successive high school summers volunteering at Sloan-Kettering, a prominent medical hospital in NY. My project focused on the isolation and detection of circulating cancer cells found in lung cancer and thyroid cancer patients. I worked on the development of a new technique that enables early detection of cancer cells using Immunomagnetic Beads using the theory of antibodies and antigen. I spent long hours working at the lab, but I enjoyed my research because it enabled me to gain a better understanding of my younger sister’s illness – ulcerative colitis, an inflammatory bowel disease that may lead to colon cancer. I am very grateful that I was given the chance to volunteer at Sloan-Kettering because in enabled me to return to the community what my parents have instilled in me – hard work, determination, and pride for who I am. My achievement has had a major beneficial impact in my community because it enables early diagnosis for cancer patients, thus allowing treatment to be assessed and available much sooner. Moreover, although I only worked with lung cancer, breast cancer, and thyroid cancer, the techniques I used can be applied for the molecular characterization of all circulating solid tumor cells, including colon cancer. Earlier detection of cancer would help Assess, Stratify, and Design Targeted Therapy for the Cancer Patient. |